Product Name: Fascaplysin chloride
Description: Fascaplysin is an inhibitor of cyclin D kinase 4/ cyclin D1 (IC50 = 0.35 μM). Fascaplysin induces caspase mediated crosstalk between apoptosis and autophagy through the inhibition of PI3K/AKT/mTOR signaling cascade in human leukemia HL-60 cells.
CAS NO: 546111-97-1 Product: Litronesib (Racemate)
Synonym: Fascaplysin; Fascaplysin chloride; NSC 622398; NSC622398; NSC-622398.
IUPAC Chemical Name: 12,13-dihydro-13-oxo-pyrido[1,2-a:3,4-b]diindol-5-ium, monochloride
In ChiKey: PWUOOJVYZQILBG-UHFFFAOYSA-NSaccharides and Glycosides inhibitors
SMILE Code: O=C1C2=C3NC4=C(C=CC=C4)C3=CC=[N+]2C5=C1C=CC=C5.[Cl-]
Appearance: Solid powder
Purity: 98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Web Site：Medchemexpress
Storage Condition: Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: 2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 – 4 C for short term (days to weeks), or -20 C for long term (months).PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22120130
Chemical Formula：C18H11ClN2O
ExactMass:
Molecular Weight: 306.749
Elemental Analysis: C, 70.48; H, 3.61; Cl, 11.56; N, 9.13; O, 5.22
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