Product Name: JNJ-28312141 featured
Description: JNJ-28312141 is an orally active CSF1R inhibitor (Colony-stimulating factor-1 receptor, CRF1R) and also a FLT3 inhibitor. CSF1R is expressed by many tumors and is a growth factor for macrophages and mediates osteoclast differentiation. JNJ-28312141 repres
CAS NO: 2306-27-6 Product: Sinensetin
Synonym: JNJ28312141; JNJ 28312141; JNJ-28312141.
IUPAC Chemical Name: 4-cyano-N-(5-(1-(2-(dimethylamino)acetyl)piperidin-4-yl)-2,3,4,5-tetrahydro-[1,1-biphenyl]-2-yl)-1H-imidazole-2-carboxamide
In ChiKey: LXR inhibitors
SMILE Code: O=C(C1=NC(C#N)=CN1)NC2=CC=C(C3CCN(C(CN(C)C)=O)CC3)C=C2C4=CCCCC4
Appearance: Solid powder
Purity: 0.98
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Medchemexpress.com
Storage Condition: Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: 5 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 – 4 C for short term (days to weeks), or -20 C for long term (months).PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22128349
Chemical Formula：C26H32N6O2
ExactMass: 460.25867
Molecular Weight: 460.57
Elemental Analysis: C, 67.80; H, 7.00; N, 18.25; O, 6.95
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