Product Name: K-7174-2HCl new featured
Description: K-7174 is a novel orally active, potent proteasome inhibitor. K-7174 exerts anti-myeloma activity in vitro and in vivo by down-regulating the expression of class I histone deacetylases. K-7174 kills bortezomib-resistant myeloma cells carrying a β5-subunit
CAS NO: 2002381-25-9 Product: APS-2-79
Synonym: K7174; K 7174; K-7174; K-7174-2HCl; K-7174 dihydrochloride.
IUPAC Chemical Name: 1,4-bis((E)-5-(3,4,5-trimethoxyphenyl)pent-4-en-1-yl)-1,4-diazepane dihydrochloride.
In ChiKey: Renin inhibitors
SMILE Code: COC1=C(OC)C(OC)=CC(/C=C/CCCN2CCN(CCC/C=C/C3=CC(OC)=C(OC)C(OC)=C3)CCC2)=C1.[H]Cl.[H]Cl
Appearance: White to off-white solid powder
Purity: 98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Web Site click
Storage Condition: Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: 2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 – 4 C for short term (days to weeks), or -20 C for long term (months).PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22129092
Chemical Formula：C33H50Cl2N2O6
ExactMass:
Molecular Weight: 640.3
Elemental Analysis: C, 61.77; H, 7.85; Cl, 11.05; N, 4.37; O, 14.96
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