Product Name: K145 HCl salt featured
Description: K145 is a selective sphingosine kinase-2 (SphK2) inhibitor and anticancer agent. K145 inhibited the activity of SphK2 in a dose-dependent manner with an IC50 of 4.30±0.06 µM. K145 also exhibited inhibitory effects on the growth of U937 cells as well as
CAS NO: 1708971-72-5 Product: FGFR4-IN-1
Synonym: K145; K-145; K 145; K145 HCl; K145 hydrochloride.
IUPAC Chemical Name: (Z)-3-(2-aminoethyl)-5-(3-(4-butoxyphenyl)propylidene)thiazolidine-2,4-dione hydrochloride
In ChiKey: RAR_RXR inhibitors
SMILE Code: O=C(N(CCN)C/1=O)SC1=C/CCC2=CC=C(OCCCC)C=C2.[H]Cl
Appearance: white solid powder
Purity: 98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Medchemexpress.com
Storage Condition: Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, and in water
Shelf Life: 2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO or water.
Stock Solution Storage: 0 – 4 C for short term (days to weeks), or -20 C for long term (months).PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22129066
Chemical Formula：C18H24N2O3S
ExactMass: 348.15076
Molecular Weight: 348.46
Elemental Analysis: C, 62.04; H, 6.94; N, 8.04; O, 13.77; S, 9.20
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