Product Name: L189 new featured
Description: L189 is a DNA ligase I, III and IV inhibitor (IC50 values are 5, 9 and 5 μM respectively) that blocks DNA binding. L189 inhibits base excision repair (BER) and non-homologous end joining (NHEJ). L189 specifically sensitizes cancer cells to DNA damage and
CAS NO: 1448754-43-5 Product: Eleclazine (hydrochloride)
Synonym: L189; L 189; L-189.
IUPAC Chemical Name: (E)-6-amino-5-(benzylideneamino)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
In ChiKey: SAKOXVNKDMWWLF-AWNIVKPZSA-NGli inhibitors
SMILE Code: O=C(C(/N=C/C1=CC=CC=C1)=C(N)N2)NC2=S
Appearance: White to off-white solid powder.
Purity: 98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Web Site click
Storage Condition: Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: 2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 – 4 C for short term (days to weeks), or -20 C for long term (months).PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22131041
Chemical Formula：C11H10N4OS
ExactMass: 246.05753
Molecular Weight: 246.29
Elemental Analysis: C, 53.64; H, 4.09; N, 22.75; O, 6.50; S, 13.02
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