Product Name: Sacubitril sodium new featured
Description: Sacubitril, also known as AHU377, is angiotensin receptor neprilysin inhibitor being studied for use in combination with valsartan for heart failure. Sacubitril is a prodrug that is activated to LBQ657 by de-ethylation via esterases. LBQ657 inhibits the e
CAS NO: 1253452-78-6 Product: KS176
Synonym: Sacubitril sodium; AHU377; AHU 377; AHU-377; LCZ696.
IUPAC Chemical Name: sodium 4-(((2S,4R)-1-([1,1-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoate
In ChiKey: RRTBVEJIZWGATF-JKSHRDEXSA-MCOX inhibitors
SMILE Code: O=C([O-])CCC(N[C@@H](C[C@@H](C)C(OCC)=O)CC1=CC=C(C2=CC=CC=C2)C=C1)=O.[Na+]
Appearance: Brown solid powder
Purity: 98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Web Site：Medchemexpress
Storage Condition: Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: 2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 – 4 C for short term (days to weeks), or -20 C for long term (months).PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22145851
Chemical Formula：C24H28NNaO5
ExactMass:
Molecular Weight: 433.4798
Elemental Analysis: C, 66.50; H, 6.51; N, 3.23; Na, 5.30; O, 18.45
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