Product Name: U0126-EtOH
Description: U0126-EtOH is a highly selective inhibitor of MEK1/2 with IC50 of 0.07 μM/0.06 μM, 100-fold higher affinity for ΔN3-S218E/S222D MEK than PD98059. This inhibition of MEK1/2 is noncompetitive with ERK and ATP.
CAS NO: 1354744-91-4 Product: Naloxegol (oxalate)
Synonym: U0126-EtOH; U0126EtOH; U0126 EtOH.
IUPAC Chemical Name: (2Z,3Z)-2,3-bis(amino((2-aminophenyl)thio)methylene)succinonitrile compound with ethanol (1:1)
In ChiKey: CFQULUVMLGZVAF-OYJDLGDISA-NDipeptidyl Peptidase inhibitors
SMILE Code: CCO.C1=CC=C(C(=C1)N)SC(=C(C#N)C(=C(N)SC2=CC=CC=C2N)C#N)N
Appearance: Solid powder
Purity: 98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Web Site：Medchemexpress
Storage Condition: Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: 2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 – 4 C for short term (days to weeks), or -20 C for long term (months).PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22148994
Chemical Formula：C20H22N6OS2
ExactMass: 426.1297
Molecular Weight: 426.56
Elemental Analysis: C, 56.32; H, 5.20; N, 19.70; O, 3.75; S, 15.03
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