Product Name: XEN445 featured
Description: XEN445 is potent and selective endothelial lipase inhibitor, that showed good ADME and PK properties, and demonstrated in vivo efficacy in raising plasma HDLc concentrations in mice. Endothelial lipase (EL) activity has been implicated in HDL metabolism a
CAS NO: 845272-21-1 Product: Varlitinib
Synonym: XEN445; XEN 445; XEN-445.
IUPAC Chemical Name: (S)-2-(3-(pyridin-2-ylmethoxy)pyrrolidin-1-yl)-5-(trifluoromethyl)benzoic acid
In ChiKey: GPR40 inhibitors
SMILE Code: O=C(O)C1=CC(C(F)(F)F)=CC=C1N2C[C@@H](OCC3=NC=CC=C3)CC2
Appearance: white to off-white solid powder
Purity: 98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Medchemexpress
Storage Condition: Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: 2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 – 4 C for short term (days to weeks), or -20 C for long term (months).PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22153556
Chemical Formula：C18H17F3N2O3
ExactMass: 366.11913
Molecular Weight: 366.33
Elemental Analysis: C, 59.02; H, 4.68; F, 15.56; N, 7.65; O, 13.10
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