Atory infrastructure and funding. All authors study and approved the final

Atory infrastructure and funding. All authors read and approved the final manuscript. Competing interests The authors declare that they have no competing interests. Author details 1 Department of Animal Physiology, Faculty of Biotechnology and Food Sciences, Slovak University of Agriculture in Nitra, Tr. A. Hlinku 2, Nitra 94976, Slovakia. 2AgroBioTech Research Centre, Slovak University of Agriculture in Nitra, Tr. A. Hlinku two, Nitra 94976, Slovakia. 3Department of Botany and Genetics, Faculty of Natural Sciences, Constantine the Philosopher University in Nitra, N rezie ml eze 91, Nitra 94974, Slovakia. 4Department of General Biology, Faculty of Organic Sciences, Gulistan State University, 4th Microrayon, Guliston 120100, Syrdarya, Uzbekistan. Received: 24 March 2016 Accepted: 24 AugustReferences 1. Bansal AK, Bilaspuri GS. Impacts of oxidative tension and antioxidants on semen functions. Vet Med Int. 2010;2011(2011):7. doi:10.4061/2011/686137. hindawi/journals/vmi/2011/686137/. two. Du Plessis SS, Agarwal A, Halabi J, Tvrda E. Modern evidence around the physiological function of reactive oxygen species in human sperm function. J Help Reprod Genet. 2015;32(four):509sirtuininhibitor20. three. Sikka SC. Oxidative stress and part of antioxidants in standard and abnormal sperm function. Front Biosci. 1996;1:e78sirtuininhibitor6. 4. Garrido N, Meseguer M, Simon C, Pellicer A, Remohi J. Pro-oxidative and anti-oxidative imbalance in human semen and its relation with male fertility. Asian J Androl. 2004;six(1):59sirtuininhibitor5. 5. Desai N, Sharma R, Makker K, Sabanegh E, Agarwal A. Physiologic and pathologic levels of reactive oxygen species in neat semen of infertile guys. Fertil Steril. 2009;92(5):1626sirtuininhibitor631. 6. Aitken RJ, Clarkson JS, Fishel S. Generation of reactive oxygen species, lipid peroxidation, and human sperm function. Biol Reprod. 1989;41(1):183sirtuininhibitor97. 7. Aitken RJ, Koppers AJ. Apoptosis and DNA damage in human spermatozoa. Asian J Androl. 2011;13(1):36sirtuininhibitor2. 8. Baker MA, Aitken RJ. Reactive oxygen species in spermatozoa: methods for monitoring and significance for the origins of genetic disease and infertility. Reprod Biol Endocrinol. 2005;3:67. 9. Lewis SE, Aitken RJ. DNA damage to spermatozoa has impacts on fertilization and pregnancy. Cell Tissue Res. 2005;322:33sirtuininhibitor1. 10. Twigg J, Fulton N, Gomez E, Irvine DS, Aitken RJ. Analysis on the effect of intracellular reactive oxygen species generation around the structural and functional integrity of human spermatozoa: lipid peroxidation, DNA fragmentation and effectiveness of antioxidants. Hum Reprod. 1998;13(6):1429sirtuininhibitor436. 11. Sheweita SA, Tilmisany AM, Al-Sawaf H.HDAC6 Protein manufacturer Mechanisms of male infertility: function of antioxidants.NAMPT Protein custom synthesis Curr Drug Metab.PMID:23907051 2005;6(five):495sirtuininhibitor01. 12. Bramley PM. Is lycopene beneficial to human healthsirtuininhibitor Phytochemistry. 2000;54(3):233sirtuininhibitor36. 13. Rao LG, Guns E, Rao AV. Lycopene: Its role in human wellness and illness. Agro Food Industry Hi-Tech. 2003;25sirtuininhibitor0. health-mall.in/files_hl/ lycopene_its_role_human_health.pdf. 14. Gupta NP, Kumar R. Lycopene therapy in idiopathic male infertility-a preliminary report. Int Urol Nephrol. 2002;34(3):369sirtuininhibitor72.15. Filipcikova R, Oborna I, Brezinova J, Novotny J, Wojewodka G, De Sanctis JB. Lycopene improves the distorted ratio in between AA/DHA within the seminal plasma of infertile males and increases the likelihood of profitable pregnanc.