Eculizumab | bet-bromodomain.com

Product Name :
Eculizumab

CAS :
219685-50-4

Features and Advantages :
NameEculizumabCAS NO.219685-50-4TypeWhole antibodySourceHumanized (from mouse)TargetComplement protein C5CloneMonocloneMolecular Weight148 kDaAntibody FormPurified immunoglobulinPhysical FormSolutionPlace of OriginUSAStorageSealed and stored at -70±15℃, away from light

Specifications:
2mg/tube, 5mg/tube, 10mg/tube, 20mg/tube

Introduction:
This product is the biosimilar of Eculizumab (219685-50-4), which is a recombinant humanized monoclonal IgG2/4κ antibody produced by Chinese hamster ovary cell culture and purified by standard bioprocess technology. Eculizumab contains human constant regions from human IgG2 sequences and human IgG4 sequences and murine complementarity-determining regions grafted onto the human framework light- and heavy-chain variable regions. The biosimilar is composed of two 448 amino acid heavy chains and two 214 amino acid light chains and has a molecular weight of approximately 148 kDa.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: bet-bromodomain.

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