Product Name :
Orotic acid, anhydrous, 97%
Synonym:
IUPAC Name :
2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid
CAS NO.:
65-86-1
Molecular Weight :
Molecular formula:
C5H4N2O4
Smiles:
OC(=O)C1=CC(=O)NC(=O)N1
Description:
Orotic acid is an intermediate in de novo pyrimidine biosynthesis that may be used to study the specificity and kinetics of orotate phosphoribosyltransferase (OPRT) which catalyzes the reversible phosphoribosyl transfer from 5?-phospho-α-d-ribose 1?-diphosphate (PRPP) to orotic acid (OA), forming pyrophosphate and orotidine 5?-monophosphate (OMP). It is used as a starting material for the potential commercial bioproduction of uridine 5?-monophosphate (UMP) by microbes such as Corynebacterium ammoniagenes (ATCC 6872) or Saccharomyces cerevisiae.Streptomycin sulfate It may be used to study the AMPK/SREBP-1 dependent cell signaling pathway and transcription regulation mechanisms that induce hepatic lipogenesis.Wogonin PMID:24455443
