Product Name :
PI3K-IN-30
Description:
PI3K-IN-30 (compound 6d) is a potent PI3K inhibitor with IC50s of 5.1, 136, 30.7 and 8.9 nM for PI3Kα, PI3Kβ, PI3Kγ and PI3Kδ, respectively.
CAS:
2281803-22-1
Molecular Weight:
449.45
Formula:
C20H25F2N7O3
Chemical Name:
Smiles :
COCCN(CCO)C1=NC(=NC(=N1)N1CCOCC1)N1C(=NC2=CC=CC=C12)C(F)F
InChiKey:
DTTGBWQUOGWGMZ-UHFFFAOYSA-N
InChi :
InChI=1S/C20H25F2N7O3/c1-31-11-7-27(6-10-30)18-24-19(28-8-12-32-13-9-28)26-20(25-18)29-15-5-3-2-4-14(15)23-17(29)16(21)22/h2-5,16,30H,6-13H2,1H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
PI3K-IN-30 (compound 6d) is a potent PI3K inhibitor with IC50s of 5.1, 136, 30.7 and 8.{{E1210} medchemexpress|{E1210} Anti-infection|{E1210} Biological Activity|{E1210} Description|{E1210} supplier|{E1210} Autophagy} 9 nM for PI3Kα, PI3Kβ, PI3Kγ and PI3Kδ, respectively.{{Anti-Mouse 4-1BB Antibody} medchemexpress|{Anti-Mouse 4-1BB Antibody} TNF Receptor|{Anti-Mouse 4-1BB Antibody} Protocol|{Anti-Mouse 4-1BB Antibody} Purity|{Anti-Mouse 4-1BB Antibody} supplier|{Anti-Mouse 4-1BB Antibody} Cancer} |Product information|CAS Number: 2281803-22-1|Molecular Weight: 449.PMID:23672196 45|Formula: C20H25F2N7O3|Smiles: COCCN(CCO)C1=NC(=NC(=N1)N1CCOCC1)N1C(=NC2=CC=CC=C12)C(F)F|InChiKey: DTTGBWQUOGWGMZ-UHFFFAOYSA-N|InChi: InChI=1S/C20H25F2N7O3/c1-31-11-7-27(6-10-30)18-24-19(28-8-12-32-13-9-28)26-20(25-18)29-15-5-3-2-4-14(15)23-17(29)16(21)22/h2-5,16,30H,6-13H2,1H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: To be determined|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Van Dort ME, et al. Structural effects of morpholine replacement in ZSTK474 on Class I PI3K isoform inhibition: Development of novel MEK/PI3K bifunctional inhibitors. Eur J Med Chem. 2022;229:113996.Products are for research use only. Not for human use.|
