Product Name :
Dibenamine hydrochloride
Description:
Dibenamine hydrochloride is a competitive and irreversible adrenergic blocking agent and is known to modify the pharmacological effects of epinephrine. Dibenamine hydrochloride cause a significant increase in the rate of destruction of I-epinephrine in the mouse.
CAS:
55-43-6
Molecular Weight:
296.23
Formula:
C16H19Cl2N
Chemical Name:
dibenzyl(2-chloroethyl)amine hydrochloride
Smiles :
Cl.ClCCN(CC1C=CC=CC=1)CC1C=CC=CC=1
InChiKey:
LZXCEBPGNFLHEQ-UHFFFAOYSA-N
InChi :
InChI=1S/C16H18ClN.ClH/c17-11-12-18(13-15-7-3-1-4-8-15)14-16-9-5-2-6-10-16;/h1-10H,11-14H2;1H
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Hypericin} medchemexpress|{Hypericin} Epigenetics|{Hypericin} Protocol|{Hypericin} In stock|{Hypericin} supplier|{Hypericin} Epigenetics}
Shelf Life:
≥12 months if stored properly.{{Letrozole} web|{Letrozole} Metabolic Enzyme/Protease|{Letrozole} Technical Information|{Letrozole} Purity|{Letrozole} manufacturer|{Letrozole} Epigenetics}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Dibenamine hydrochloride is a competitive and irreversible adrenergic blocking agent and is known to modify the pharmacological effects of epinephrine. Dibenamine hydrochloride cause a significant increase in the rate of destruction of I-epinephrine in the mouse.|Product information|CAS Number: 55-43-6|Molecular Weight: 296.23|Formula: C16H19Cl2N|Chemical Name: dibenzyl(2-chloroethyl)amine hydrochloride|Smiles: Cl.ClCCN(CC1C=CC=CC=1)CC1C=CC=CC=1|InChiKey: LZXCEBPGNFLHEQ-UHFFFAOYSA-N|InChi: InChI=1S/C16H18ClN.ClH/c17-11-12-18(13-15-7-3-1-4-8-15)14-16-9-5-2-6-10-16;/h1-10H,11-14H2;1H|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 125 mg/mL (421.97 mM; Need ultrasonic). H2O : 33.33 mg/mL (112.51 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:23255394 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Dibenamine (100 nM-10 μM) attenuates the degree of cocaine-induced increase in sensitivity to acetylcholine without any effect on acetylcholine-contraction in isolated vas deferens of guinea pig. Additionally, the degree of dibenamine-induced inhibition dependent on the concentration of dibenamine and inversely related to the concentration of cocaine.|In Vivo:|Dibenamine hydrochloride (subcutaneous injection; 25 mg/kg; 48 and 24 hr before the administration of CCl4) decreases the CHCl3, levels at 2 and 6 hr by 30-50 percent, but did not appreciably affect the half-life of CHCl3, in the liver.Pretreatment with Dibenamine apparently slows the conversion of Ccl4 to CHCL3.|Products are for research use only. Not for human use.|
