Product Name :
MELK-IN-1
Description:
MELK-IN-1 is a potent inhibitor of maternal embryonic leucine zipper kinase (MELK) with an IC50 and a Ki of 3 nM and 0.39 nM, respectively.
CAS:
2095596-44-2
Molecular Weight:
539.62
Formula:
C31H33N5O4
Chemical Name:
methyl 2-hydroxy-3-[({4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl}imino)(phenyl)methyl]-1H-indole-5-carboxylate
Smiles :
CN1CCN(CC(=O)N(C)C2C=CC(=CC=2)N=C(C2=C(O)NC3=CC=C(C=C32)C(=O)OC)C2C=CC=CC=2)CC1
InChiKey:
XIMRJNBUWJTLAL-UUDCSCGESA-N
InChi :
InChI=1S/C31H33N5O4/c1-34-15-17-36(18-16-34)20-27(37)35(2)24-12-10-23(11-13-24)32-29(21-7-5-4-6-8-21)28-25-19-22(31(39)40-3)9-14-26(25)33-30(28)38/h4-14,19,33,38H,15-18,20H2,1-3H3/b32-29+
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.{{Danavorexton} site|{Danavorexton} Activator|{Danavorexton} TGF-beta/Smad|{Danavorexton} Technical Information|{Danavorexton} References|{Danavorexton} manufacturer}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Idelalisib} medchemexpress|{Idelalisib} Autophagy|{Idelalisib} Purity & Documentation|{Idelalisib} In stock|{Idelalisib} manufacturer|{Idelalisib} Epigenetic Reader Domain}
Additional information:
MELK-IN-1 is a potent inhibitor of maternal embryonic leucine zipper kinase (MELK) with an IC50 and a Ki of 3 nM and 0.PMID:23546012 39 nM, respectively.|Product information|CAS Number: 2095596-44-2|Molecular Weight: 539.62|Formula: C31H33N5O4|Chemical Name: methyl 2-hydroxy-3-[({4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl}imino)(phenyl)methyl]-1H-indole-5-carboxylate|Smiles: CN1CCN(CC(=O)N(C)C2C=CC(=CC=2)N=C(C2=C(O)NC3=CC=C(C=C32)C(=O)OC)C2C=CC=CC=2)CC1|InChiKey: XIMRJNBUWJTLAL-UUDCSCGESA-N|InChi: InChI=1S/C31H33N5O4/c1-34-15-17-36(18-16-34)20-27(37)35(2)24-12-10-23(11-13-24)32-29(21-7-5-4-6-8-21)28-25-19-22(31(39)40-3)9-14-26(25)33-30(28)38/h4-14,19,33,38H,15-18,20H2,1-3H3/b32-29+|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|