Product Name :
LY 2886721 Hydrochloride
Description:
LY 2886721 Hydrochloride is a potent and selective β-secretase inhibitor.
CAS:
1262036-49-6
Molecular Weight:
426.87
Formula:
C18H17ClF2N4O2S
Chemical Name:
N-(3-((4aS,7aS)-2-amino-4a,5-dihydro-4H-furo[3,4-d][1,3]thiazin-7a(7H)-yl)-4-fluorophenyl)-5-fluoropicolinamide hydrochloride
Smiles :
Cl.NC1=N[C@]2(COC[C@H]2CS1)C1=CC(=CC=C1F)NC(=O)C1=CC=C(F)C=N1
InChiKey:
JHHMCINLHBUFHB-GHDSXOKHSA-N
InChi :
InChI=1S/C18H16F2N4O2S.{{Narasin} MedChemExpress|{Narasin} NF-κB|{Narasin} Epigenetics|{Narasin} Biological Activity|{Narasin} Formula|{Narasin} manufacturer} ClH/c19-11-1-4-15(22-6-11)16(25)23-12-2-3-14(20)13(5-12)18-9-26-7-10(18)8-27-17(21)24-18;/h1-6,10H,7-9H2,(H2,21,24)(H,23,25);1H/t10-,18-;/m0.{{Sapienic acid} MedChemExpress|{Sapienic acid} Bacterial|{Sapienic acid} Activator|{Sapienic acid} Purity & Documentation|{Sapienic acid} Data Sheet|{Sapienic acid} supplier} /s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:24377291
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
LY 2886721 Hydrochloride is a potent and selective β-secretase inhibitor.|Product information|CAS Number: 1262036-49-6|Molecular Weight: 426.87|Formula: C18H17ClF2N4O2S|Synonym:|LY 2886721 Hydrochloride|BS-14794|LY-2886721 hydrochloride|1262036-49-6|UNII-HW8GJY7V7R|HW8GJY7V7R|N-(3-((4aS,7aS)-2-Amino-4a,5,7,7a-tetrahydro-4H-furo[3,4-d][1,3]thiazin-7a-yl)-4-fluorophenyl)-5-fluoropicolinamide hydrochloride|SCHEMBL970474|DTXSID10155116|BCP24785|Q27280128|Chemical Name: N-(3-((4aS,7aS)-2-amino-4a,5-dihydro-4H-furo[3,4-d][1,3]thiazin-7a(7H)-yl)-4-fluorophenyl)-5-fluoropicolinamide hydrochloride|Smiles: Cl.NC1=N[C@]2(COC[C@H]2CS1)C1=CC(=CC=C1F)NC(=O)C1=CC=C(F)C=N1|InChiKey: JHHMCINLHBUFHB-GHDSXOKHSA-N|InChi: InChI=1S/C18H16F2N4O2S.ClH/c19-11-1-4-15(22-6-11)16(25)23-12-2-3-14(20)13(5-12)18-9-26-7-10(18)8-27-17(21)24-18;/h1-6,10H,7-9H2,(H2,21,24)(H,23,25);1H/t10-,18-;/m0./s1|Technical Data|Appearance: Solid Power.|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Soluble in DMSO|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined.|HS Tariff Code: 382200|References:|May et al (2015) The potent BACE1 inhibitor LY2886721 elicits robust central Aβ pharmacodynamic responses in mice, dogs and humans. J.Neurosci. 35 1199 PMID: 25609634Products are for research use only. Not for human use.|
