Product Name :
JBSNF-000028 TFA
CAS No.:
Purity :
99.47%
Shipping:
Room temperature in the continental U.S. Other areas may vary.
Storage :
In solvent: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
SMILES:
CN1CC2=C3C(CCN3C1=N)=CC=C2.FC(F)(C(O)=O)F
Product Description :
JBSNF-000028 TFA is an orally active nicotinamide N-methyltransferase (NNMT) inhibitor with IC50s of 0.033 μM, 0.19 μM and 0.{{849214-04-6} MedChemExpress|{849214-04-6} Biological Activity|{849214-04-6} In Vivo|{849214-04-6} custom synthesis} 21 μM against human NNMT (hNNMT), monkey NNMT (mkNNMT), and mouse NNMT (mNNMT), respectively.{{2452464-73-0} medchemexpress|{2452464-73-0} Purity & Documentation|{2452464-73-0} Purity|{2452464-73-0} custom synthesis} JBSNF-000028 TFA can be used for the research of metabolic disorders.
Formula:
C13H14F3N3O2
Molecular Weight :
301.26
Synonyms:
Additional Information:
|Formula C13H14F3N3O2 ; |Molecular Weight 301.26 ; |SMILES CN1CC2=C3C(CCN3C1=N)=CC=C2.FC(F)(C(O)=O)F ; |Target Others ; |Product Description JBSNF-000028 TFA is an orally active nicotinamide N-methyltransferase (NNMT) inhibitor with IC50s of 0.PMID:31334979 033 μM, 0.19 μM and 0.21 μM against human NNMT (hNNMT), monkey NNMT (mkNNMT), and mouse NNMT (mNNMT), respectively. JBSNF-000028 TFA can be used for the research of metabolic disorders. ; |Format Solid ; |Color White to off-white ; |Purity 99.47% ; |Shipping Room temperature in the continental U.S. Other areas may vary. ; |Storage In solvent: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) ; |Solubility Overview Soluble in DMSO
