Product Name :
BAY-677
Description:
BAY-677 is an inactive control for BAY-678. BAY-678 is an orally bioavailable, highly potent, selective and cell-permeable inhibitor of human neutrophil elastase (HNE), with an IC50 of 20 nM. BAY-678 is also nominated as a chemical probe to the public via the Structural Genomics Consortium (SGC).
CAS:
2117404-84-7
Molecular Weight:
400.35
Formula:
C20H15F3N4O2
Chemical Name:
5-[(4S)-5-acetyl-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydropyrimidin-4-yl]pyridine-2-carbonitrile
Smiles :
CC(=O)C1[C@@H](NC(=O)N(C2=CC(=CC=C2)C(F)(F)F)C=1C)C1=CN=C(C=C1)C#N
InChiKey:
PGIVGIFOWOVINL-SFHVURJKSA-N
InChi :
InChI=1S/C20H15F3N4O2/c1-11-17(12(2)28)18(13-6-7-15(9-24)25-10-13)26-19(29)27(11)16-5-3-4-14(8-16)20(21,22)23/h3-8,10,18H,1-2H3,(H,26,29)/t18-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
BAY-677 is an inactive control for BAY-678. BAY-678 is an orally bioavailable, highly potent, selective and cell-permeable inhibitor of human neutrophil elastase (HNE), with an IC50 of 20 nM. BAY-678 is also nominated as a chemical probe to the public via the Structural Genomics Consortium (SGC).|Product information|CAS Number: 2117404-84-7|Molecular Weight: 400.35|Formula: C20H15F3N4O2|Chemical Name: 5-[(4S)-5-acetyl-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydropyrimidin-4-yl]pyridine-2-carbonitrile|Smiles: CC(=O)C1[C@@H](NC(=O)N(C2=CC(=CC=C2)C(F)(F)F)C=1C)C1=CN=C(C=C1)C#N|InChiKey: PGIVGIFOWOVINL-SFHVURJKSA-N|InChi: InChI=1S/C20H15F3N4O2/c1-11-17(12(2)28)18(13-6-7-15(9-24)25-10-13)26-19(29)27(11)16-5-3-4-14(8-16)20(21,22)23/h3-8,10,18H,1-2H3,(H,26,29)/t18-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : ≥ 50 mg/mL (124.{{Scutellarin} site|{Scutellarin} Anti-infection|{Scutellarin} Protocol|{Scutellarin} In stock|{Scutellarin} manufacturer|{Scutellarin} Cancer} 89 mM).{{Isosulfan blue} medchemexpress|{Isosulfan blue} {Fluorescent Dye}|{Isosulfan blue} Purity & Documentation|{Isosulfan blue} In stock|{Isosulfan blue} custom synthesis|{Isosulfan blue} Cancer} |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:32491755 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
