Product Name :
IM-12
Sequence:
Purity:
≥98% (HPLC)
Molecular Weight:
377.4
Solubility :
Soluble in DMSO (25 mg/ml) or in 100% ethanol (5 mg/ml).
Appearance:
Orange solid.
Use/Stability :
As indicated on product label or CoA when stored as recommended. Store as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months.
Description:
GSK-3β inhibitor (IC50=53nM (enzymatic), 3.8µM (cellular)). The compound significantly increases β-catenin levels, leads to TCF-induction and promotes neuronal differentiation in human neural progenitor cells via activation of canonical Wnt signaling.
CAS :
1129669-05-1
Solubility:
Soluble in DMSO (25 mg/ml) or in 100% ethanol (5 mg/ml).
Formula:
C22H20FN3O2
Additional Information :
| Alternative Name 3-(4-Fluorophenylethylamino)-1-methyl-4-(2-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione | Appearance Orange solid.{{21679-14-1} web|{21679-14-1} Technical Information|{21679-14-1} Data Sheet|{21679-14-1} custom synthesis} | CAS 1129669-05-1 | Couple Target GSK | Couple Type Inhibitor | Formula C22H20FN3O2 | MW 377.{{2097132-94-8} medchemexpress|{2097132-94-8} Protocol|{2097132-94-8} In Vivo|{2097132-94-8} manufacturer} 4 | Purity ≥98% (HPLC) | Solubility Soluble in DMSO (25 mg/ml) or in 100% ethanol (5 mg/ml).PMID:28613730 | Unit of Measure (UM) mg
