Product Name :
Afobazole
Description:
Afobazole, also known as Fabomotizole, Obenoxazine and CM346, is an anxiolytic drug launched in Russia in the early 2000s. It produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions. Its mechanism of action remains poorly defined however, with GABAergic, NGF- and BDNF-release-promoting, MT1 receptor agonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Fabomotizole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Fabomotizole has found little clinical use outside Russia and has not been evaluated by the FDA.
CAS:
173352-21-1
Molecular Weight:
307.41
Formula:
C15H21N3O2S
Chemical Name:
6-ethoxy-2-{[2-(morpholin-4-yl)ethyl]sulfanyl}-1H-1,3-benzodiazole
Smiles :
CCOC1=CC=C2N=C(NC2=C1)SCCN1CCOCC1
InChiKey:
WWNUCVSRRUDYPP-UHFFFAOYSA-N
InChi :
InChI=1S/C15H21N3O2S/c1-2-20-12-3-4-13-14(11-12)17-15(16-13)21-10-7-18-5-8-19-9-6-18/h3-4,11H,2,5-10H2,1H3,(H,16,17)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Afobazole, also known as Fabomotizole, Obenoxazine and CM346, is an anxiolytic drug launched in Russia in the early 2000s. It produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions. Its mechanism of action remains poorly defined however, with GABAergic, NGF- and BDNF-release-promoting, MT1 receptor agonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Fabomotizole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Fabomotizole has found little clinical use outside Russia and has not been evaluated by the FDA.{{L-Ornithine} medchemexpress|{L-Ornithine} Metabolic Enzyme/Protease|{L-Ornithine} Protocol|{L-Ornithine} Data Sheet|{L-Ornithine} manufacturer|{L-Ornithine} Epigenetics} |Product information|CAS Number: 173352-21-1|Molecular Weight: 307.{{Inorganic pyrophosphatase} web|{Inorganic pyrophosphatase} Cell Cycle/DNA Damage|{Inorganic pyrophosphatase} Purity & Documentation|{Inorganic pyrophosphatase} Data Sheet|{Inorganic pyrophosphatase} manufacturer|{Inorganic pyrophosphatase} Autophagy} 41|Formula: C15H21N3O2S|Chemical Name: 6-ethoxy-2-{[2-(morpholin-4-yl)ethyl]sulfanyl}-1H-1,3-benzodiazole|Smiles: CCOC1=CC=C2N=C(NC2=C1)SCCN1CCOCC1|InChiKey: WWNUCVSRRUDYPP-UHFFFAOYSA-N|InChi: InChI=1S/C15H21N3O2S/c1-2-20-12-3-4-13-14(11-12)17-15(16-13)21-10-7-18-5-8-19-9-6-18/h3-4,11H,2,5-10H2,1H3,(H,16,17)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:24580853 |Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
