Product Name :
Atrasentan Hydrochloride
Description:
Atrasentan, also known as ABT-627, is a orally available ETA receptor antagonist with potential antineoplastic activity. As a selective antagonist of the endothelin-A (ETA) receptor, atrasentan binds selectively to the ETA receptor, which may result in inhibition of endothelin-induced angiogenesis and tumor cell proliferation.
CAS:
195733-43-8
Molecular Weight:
547.08
Formula:
C29H39ClN2O6
Chemical Name:
(2R,3R,4S)-4-(2H-1,3-benzodioxol-5-yl)-1-[(dibutylcarbamoyl)methyl]-2-(4-methoxyphenyl)pyrrolidine-3-carboxylic acid hydrochloride
Smiles :
Cl.COC1C=CC(=CC=1)[C@H]1[C@@H]([C@H](CN1CC(=O)N(CCCC)CCCC)C1=CC2OCOC=2C=C1)C(O)=O
InChiKey:
IJFUJIFSUKPWCZ-SQMFDTLJSA-N
InChi :
InChI=1S/C29H38N2O6.{{Norfluoxetine} medchemexpress|{Norfluoxetine} Membrane Transporter/Ion Channel|{Norfluoxetine} Immunology/Inflammation|{Norfluoxetine} Protocol|{Norfluoxetine} Data Sheet|{Norfluoxetine} supplier} ClH/c1-4-6-14-30(15-7-5-2)26(32)18-31-17-23(21-10-13-24-25(16-21)37-19-36-24)27(29(33)34)28(31)20-8-11-22(35-3)12-9-20;/h8-13,16,23,27-28H,4-7,14-15,17-19H2,1-3H3,(H,33,34);1H/t23-,27-,28+;/m1./s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Atrasentan, also known as ABT-627, is a orally available ETA receptor antagonist with potential antineoplastic activity. As a selective antagonist of the endothelin-A (ETA) receptor, atrasentan binds selectively to the ETA receptor, which may result in inhibition of endothelin-induced angiogenesis and tumor cell proliferation.{{Mirvetuximab} MedChemExpress|{Mirvetuximab} Antifolate|{Mirvetuximab} Technical Information|{Mirvetuximab} Formula|{Mirvetuximab} custom synthesis|{Mirvetuximab} Epigenetics} |Product information|CAS Number: 195733-43-8|Molecular Weight: 547.PMID:23664186 08|Formula: C29H39ClN2O6|Chemical Name: (2R,3R,4S)-4-(2H-1,3-benzodioxol-5-yl)-1-[(dibutylcarbamoyl)methyl]-2-(4-methoxyphenyl)pyrrolidine-3-carboxylic acid hydrochloride|Smiles: Cl.COC1C=CC(=CC=1)[C@H]1[C@@H]([C@H](CN1CC(=O)N(CCCC)CCCC)C1=CC2OCOC=2C=C1)C(O)=O|InChiKey: IJFUJIFSUKPWCZ-SQMFDTLJSA-N|InChi: InChI=1S/C29H38N2O6.ClH/c1-4-6-14-30(15-7-5-2)26(32)18-31-17-23(21-10-13-24-25(16-21)37-19-36-24)27(29(33)34)28(31)20-8-11-22(35-3)12-9-20;/h8-13,16,23,27-28H,4-7,14-15,17-19H2,1-3H3,(H,33,34);1H/t23-,27-,28+;/m1./s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
