Product Name :
Stattic
Sequence:
Purity:
≥98% (TLC)
Molecular Weight:
211.2
Solubility :
Soluble in DMSO (>25 mg/ml), 100% ethanol (10 mg/ml).
Appearance:
Pale yellow solid.
Use/Stability :
As indicated on product label or CoA when stored as recommended.115-02-6 manufacturer Store solutions at -20°C for up to 3 months.
Description:
STAT inhibitor Small molecule STAT3-specific inhibitor which blocks activation, dimerization and nuclear translocation via binding to the STAT3 SH2 domain. It is a very useful tool for exploring STAT3-mediated signaling pathways.2230820-11-6 Technical Information It blocks LPS-mediated STAT3 tyrosine phosphorylation which leads to inhibition of LPS-mediated IL-1β and IL-6 production.PMID:21563328 In primary cultures of rat neural stem cells it blocks IL-15-induced differentiation.
CAS :
19983-44-9
Solubility:
Soluble in DMSO (>25 mg/ml), 100% ethanol (10 mg/ml).
Formula:
C8H5NO4S
Additional Information :
| Alternative Name 6-Nitro[b]thiophene-1,1-dioxide | Appearance Pale yellow solid. | CAS 19983-44-9 | Couple Target STAT | Couple Type Inhibitor | Formula C8H5NO4S | MW 211.2 | Purity ≥98% (TLC) | Solubility Soluble in DMSO (>25 mg/ml), 100% ethanol (10 mg/ml). | Unit of Measure (UM) mg
