Product Name :
Protein deglycase DJ-1 against-1
Description:
Protein deglycase DJ-1 against-1, a DJ-1-binding compound, dependently targets DJ1. Protein deglycase DJ-1 against-1 penetrates through the blood brain barrier (BBB). Protein deglycase DJ-1 against-1 is used as a neuroprotective agent and has the potential for Parkinson’s disease research.
CAS:
724737-74-0
Molecular Weight:
417.46
Formula:
C24H23N3O4
Chemical Name:
3, 4, 5-trimethoxy-N-(4-8-methylimidazo[1, 2-a]pyridin-2-ylphenyl)benzamide
Smiles :
CC1=CC=CN2C=C(N=C21)C1C=CC(=CC=1)NC(=O)C1=CC(OC)=C(OC)C(=C1)OC
InChiKey:
DRVIKYTZILDXIS-UHFFFAOYSA-N
InChi :
InChI=1S/C24H23N3O4/c1-15-6-5-11-27-14-19(26-23(15)27)16-7-9-18(10-8-16)25-24(28)17-12-20(29-2)22(31-4)21(13-17)30-3/h5-14H,1-4H3,(H,25,28)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Protein deglycase DJ-1 against-1, a DJ-1-binding compound, dependently targets DJ1. Protein deglycase DJ-1 against-1 penetrates through the blood brain barrier (BBB). Protein deglycase DJ-1 against-1 is used as a neuroprotective agent and has the potential for Parkinson’s disease research.|Product information|CAS Number: 724737-74-0|Molecular Weight: 417.46|Formula: C24H23N3O4|Chemical Name: 3, 4, 5-trimethoxy-N-(4-8-methylimidazo[1, 2-a]pyridin-2-ylphenyl)benzamide|Smiles: CC1=CC=CN2C=C(N=C21)C1C=CC(=CC=1)NC(=O)C1=CC(OC)=C(OC)C(=C1)OC|InChiKey: DRVIKYTZILDXIS-UHFFFAOYSA-N|InChi: InChI=1S/C24H23N3O4/c1-15-6-5-11-27-14-19(26-23(15)27)16-7-9-18(10-8-16)25-24(28)17-12-20(29-2)22(31-4)21(13-17)30-3/h5-14H,1-4H3,(H,25,28)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 25 mg/mL (59.Oligomycin Biological Activity 89 mM; ultrasonic and adjust pH to 7 with NaOH).Levosimendan web |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:32579487 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|Protein deglycase DJ-1 against-1 (compound-23; 1 mg/kg; IP; pretreatment one hour; daily; for 4 days) significantly restores MPTP induced locomotion, dopaminergic neuronal cell death and dopamine content in DJ-1(+/+) mice but not in DJ-1(-/-) mice.|Products are for research use only. Not for human use.|
