Product Name :
Motesanib Diphosphate
Description:
Motesanib, also known as AMG-706, is the orally bioavailable multiple-receptor tyrosine kinase inhibitor with potential antineoplastic activity. Motesanib selectively targets and inhibits vascular endothelial growth factor (VEGFR), platelet-derived growth factor (PDGFR), kit, and Ret receptors, thereby inhibiting angiogenesis and cellular proliferation.
CAS:
857876-30-3
Molecular Weight:
569.44
Formula:
C22H29N5O9P2
Chemical Name:
N-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(pyridin-4-yl)methyl]aminopyridine-3-carboxamide; bis(phosphoric acid)
Smiles :
CC1(C)CNC2=CC(=CC=C12)NC(=O)C1=CC=CN=C1NCC1C=CN=CC=1.OP(O)(O)=O.OP(O)(O)=O
InChiKey:
ONDPWWDPQDCQNJ-UHFFFAOYSA-N
InChi :
InChI=1S/C22H23N5O.2H3O4P/c1-22(2)14-26-19-12-16(5-6-18(19)22)27-21(28)17-4-3-9-24-20(17)25-13-15-7-10-23-11-8-15;2*1-5(2,3)4/h3-12,26H,13-14H2,1-2H3,(H,24,25)(H,27,28);2*(H3,1,2,3,4)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.(+)-Kavain supplier
Shelf Life:
≥360 days if stored properly.Mizoribine Epigenetic Reader Domain
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:33084512
Additional information:
Motesanib, also known as AMG-706, is the orally bioavailable multiple-receptor tyrosine kinase inhibitor with potential antineoplastic activity. Motesanib selectively targets and inhibits vascular endothelial growth factor (VEGFR), platelet-derived growth factor (PDGFR), kit, and Ret receptors, thereby inhibiting angiogenesis and cellular proliferation.|Product information|CAS Number: 857876-30-3|Molecular Weight: 569.44|Formula: C22H29N5O9P2|Chemical Name: N-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(pyridin-4-yl)methyl]aminopyridine-3-carboxamide; bis(phosphoric acid)|Smiles: CC1(C)CNC2=CC(=CC=C12)NC(=O)C1=CC=CN=C1NCC1C=CN=CC=1.OP(O)(O)=O.OP(O)(O)=O|InChiKey: ONDPWWDPQDCQNJ-UHFFFAOYSA-N|InChi: InChI=1S/C22H23N5O.2H3O4P/c1-22(2)14-26-19-12-16(5-6-18(19)22)27-21(28)17-4-3-9-24-20(17)25-13-15-7-10-23-11-8-15;2*1-5(2,3)4/h3-12,26H,13-14H2,1-2H3,(H,24,25)(H,27,28);2*(H3,1,2,3,4)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
