Product Name: H3B-6527 new featured
Description: H3B-6527 is a potent and orally active FGFR4 inhibitor with potential antineoplastic activity. Upon administration, H3B-6527 specifically binds to and blocks FGFR4. This prevents the activation of FGFR4, inhibits FGFR4-mediated signaling and leads to an i
CAS NO: 890128-81-1 Product: BFH772
Synonym: H3B-6527; H3B 6527; H3B6527.
IUPAC Chemical Name: N-{2-[(6-{[(2,6-Dichloro-3,5-dimethoxyphenyl)carbamoyl](methyl)amino}-4-pyrimidinyl)amino]-5-(4-ethyl-1-piperazinyl)phenyl}acrylamide
In ChiKey: MBWRLLRCTIYXDW-UHFFFAOYSA-NEpigenetic Reader Domain inhibitors
SMILE Code: C=CC(NC1=CC(N2CCN(CC)CC2)=CC=C1NC3=NC=NC(N(C(NC4=C(Cl)C(OC)=CC(OC)=C4Cl)=O)C)=C3)=O
Appearance: Solid powder
Purity: 98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Medchemexpress.com
Storage Condition: Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: 2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 – 4 C for short term (days to weeks), or -20 C for long term (months).PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22123511
Chemical Formula：C29H34Cl2N8O4
ExactMass: 628.208
Molecular Weight: 629.543
Elemental Analysis: C, 55.33; H, 5.44; Cl, 11.26; N, 17.80; O, 10.17
bet-bromodomain.com
BET Bromodomain Inhibitor
