Product Name: TAK285-Iodo
Description: TAK285-Iodo is an analogue of TAK285, in which the trifluoro group is replaced by iodo. TAK-285 is a novel dual erbB protein kinase inhibitor that specifically targets human epidermal growth factor receptor (EGFR) and HER2. TAK-285 is currently being dev
CAS NO: 1223405-08-0 Product: LOXO-101 (sulfate)
Synonym: TAK285-Iodo; TAK-285-Iodo; TAK 285-Iodo; TAK285 derative.
IUPAC Chemical Name: N-(2-(4-((3-chloro-4-(3-iodophenoxy)phenyl)amino)-5H-pyrrolo[3,2-d]pyrimidin-5-yl)ethyl)-3-hydroxy-3-methylbutanamide
In ChiKey: ATP Citrate Lyase inhibitors
SMILE Code: CC(O)(CC(NCCN1C=CC2=NC=NC(NC3=CC=C(C(Cl)=C3)OC4=CC=CC(I)=C4)=C21)=O)C
Appearance: Solid powder
Purity: 98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Web Site click
Storage Condition: Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: 2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 – 4 C for short term (days to weeks), or -20 C for long term (months).PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22148276
Chemical Formula：C25H25ClIN5O3
ExactMass: 605.0691
Molecular Weight: 605.8615
Elemental Analysis: C, 49.56; H, 4.16; Cl, 5.85; I, 20.95; N, 11.56; O, 7.92
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