Product Name: YK-4-279
Description: YK-4-279 is a ETV1 inhibitor, which inhibitor protein-protein interactions between ES-FLI1 and RHA.YK-4-279 effectively antagonizes EWS-FLI1 induced leukemia in a transgenic mouse model. YK-4-279 demonstrates specificity in targeting the oncogene EWS-FLI1
CAS NO: 1297538-32-9 Product: ODM-201
Synonym: YK-4-279; YK4-279; YK 4-279; YK-4279; YK4279; YK 4279.
IUPAC Chemical Name: 4,7-dichloro-1,3-dihydro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-2H-indole-2-one
In ChiKey: ERK inhibitors
SMILE Code: O=C1NC2=C(C(Cl)=CC=C2Cl)C1(O)CC(C3=CC=C(OC)C=C3)=O
Appearance: Solid powder
Purity: 98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Medchemexpress.com
Storage Condition: Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: 2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 – 4 C for short term (days to weeks), or -20 C for long term (months).PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22155285
Chemical Formula：C17H13Cl2NO
ExactMass: 365.0222
Molecular Weight: 366.194
Elemental Analysis: C, 55.76; H, 3.58; Cl, 19.36; N, 3.83; O, 17.48
bet-bromodomain.com
BET Bromodomain Inhibitor
