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January 18, 2017Updated January 18, 2017

In eukaryotic cells, monitoring of the ER lumen and signaling through the canonical branches of the UPR are mediated by three ER-resident transmembrane proteins

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In this paradigm, the downregulation of GATA4 and CARP contributes in part to this...

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January 17, 2017Updated January 17, 2017

Migration of smooth muscle cells from the media to the intimal region is another important component of vascular lesion formation

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The outcomes confirmed that DIM had no unfavorable influence on endothelial mobile viability.This outcome...

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January 16, 2017Updated January 16, 2017

Downregulation by siRNA of target genes was performed using the basic NucleofectorH kit for primary smooth muscle cells

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Primers utilised to determine the expression of SLC30A/ZnTs zinc transporters are described in Table...

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January 12, 2017Updated January 12, 2017

Insulin hypersecretion mostly thought to result from insulin resistance, has also been shown to cause insulin resistance as demonstrated in rodents overexpressing the human insulin gene

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From our info, it seems that the induction of Mcl-1 protein in IBV-infected cells...

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January 11, 2017Updated January 11, 2017

However, candidiasis can sometimes result in serious opportunistic infections when the immune system is compromised, and is an important cause of morbidity and mortality in immunocompromised patients with diseases such the human immunodeficiency virus

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Expression of p-Src, E-cadherin and Vimentin in HNSCCs transfected with either Src-overexpressing#alpha-Asarone randurls[1|1|,|Money Site...

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January 10, 2017Updated January 10, 2017

Electrodes were accepted for use in the experiments, when their response exceeded 50 mV per unit change in pH

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The cRNA was purified with the RNeasy MinElute Cleanup Package (Qiagen GmbH, Hilden, Germany)...

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January 9, 2017Updated January 9, 2017

Thus, the absence of an increase in the active forms of caspases-3 and -7 as well as caspase-1 is highly consistent with the elevated caspase activity in Pt1 cells being an outcome of increased caspase-4 activation

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In examining the Arteether overall adjustments in the Pt1 transcriptome we confirmed that a...

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January 6, 2017Updated January 6, 2017

Hippo/MST signaling pathway has been delineated as a tumor suppressor pathway, which has been implicated in the diverse biological processes including cell proliferation

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Hippo/MST signaling pathway has been delineated as a tumor suppressor pathway, which has been...

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January 5, 2017Updated January 5, 2017

Note that while GC treatment downregulates cyclin D1 protein expression, the treatment results in a concomitant increase in the levels of the cell cycle inhibitor

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Note that even though GC treatment method downregulates cyclin D1 protein expression, the treatment...

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January 4, 2017Updated January 4, 2017

PELP1 recruitment to the nucleolus during stages of active Pol I transcription, and its ability to regulate ribosomal promoter activity and rRNA expression suggest that PELP1 has potential to function as a coregulator of Pol I transcription

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Previous studies identified a number of regulatory locations in the rDNA promoter , which...